基本情况
李红光，香港浸会大学博士、博士后，五邑大学生物科技与大健康学院教师。研究方向为荧光小分子探针、镧系金属配合物及纳米材料的设计与生物医药应用，其主要包括肿瘤细胞内过度表达的相关蛋白的共价标记，亚细胞的选择性成像，肿瘤靶向药物释放与成像等。
联系方式
地址: 广东江门市东成村22号五邑大学生物科技与大健康学院
邮编：529020
E-mail: wyuchemlihg@126.com；lihg@wyu.edu.cn
教育经历
2009年获西北师范大学化学专业学士学位
2016年获香港浸会大学哲学博士学位（专业：生物无机化学）
工作经历
2009年07月-2011年06月，在北京大学深圳研究生院任研究助理
2011年07月-2012年06月，在香港浸会大学任研究助理
2016年05月-2018年05月，在香港浸会大学做博士后
2018年06月-至今，在五邑大学生物科技与大健康学院从事教学、科研工作
讲授课程
本科生：《物理化学》，《无机及分析化学》
科研方向
小分子荧光探针的设计与生物医药应用；
镧系金属配合物及纳米材料的设计与生物医药应用；
超分子荧光聚集体的光学性能与生物医药应用。
论文及专利
1) H. Li, C. Xie, R. Lan, S. Zha, C.-F. Chan, W.-Y. Wong, K.-L. Ho, B. D. Chan, Y. Luo, J.-X. Zhang, G.-L. Law, W. C. S. Tai, J.-C. G. Bunzli, K.-L. Wong, ‘A smart europium-ruthenium complex as anticancer prodrug: controllable drug release and real-time monitoring under different light excitations’ Journal of Medicinal Chemistry, 2017, 60, 8923. (影响因子 = 6.259；中科院JCR分区：药物化学1区)
2) H. Li, R. Lan, C.-F. Chan, G. Bao, C. Xie, P.-H. Chu, S. Zha, W. C. S. Tai, J.-X. Zhang, K.-L. Wong, ‘A luminescent lanthanide approach towards direct visualization of primary cilia in living cells’ Chemical Communications, 2017,53, 7084. (影响因子 = 6.319；中科院JCR分区：化学1区)
3) H. Li, B. I. Harriss, A. Phinikaridou, S. Lacerda, G. Ramniceanu, B.-T. Doan, K.-L. Ho, C.-F. Chan, W.-S. Lo, R. M. Botnar, R. Lan, C. Richard, G.-L. Law, N. J. Long, K.-L. Wong, ‘Gadolinium and platinum in tandem: real-time multi-modal monitoring of drug delivery by MRI and fluorescence’ Nanotheranostics, 2017, 1, 186.
4) H. Li, R. Lan, C.-F. Chan, L. Jiang, L. Dai, D. W J Kwong, M. H.-W. Lam, K.-L. Wong, ‘Real-time in situ monitoring via europium emission of the photo-release of antitumor cisplatin from a Eu-Pt complex’, Chemical Communications, 2015, 51, 14022. (影响因子 = 6.319；中科院JCR分区：化学1区)
5) H. Li, C.-F. Chan, W.-L. Chan, S. Lear, S. L. Cobb, N.-K. Mak, T. C.-K. Lau, R. Lan, W.-K. Wong, K.-L. Wong, ‘Monitoring and inhibition of Plk1: amphiphilic porphyrin conjugated Plk1 specific peptides for its imaging and anti-tumor function’, Organic & Biomolecular Chemistry, 2014, 12, 5876. (影响因子 = 3.564；中科院JCR分区：化学2区)
6) H. Li, F. L. Chadbourne, R. Lan, C.-F. Chan, W.-L. Chan, G.-L. Law, C.-S. Lee, S. L. Cobb, K.-L. Wong, ‘Real time detection of cell cycle regulator cyclin A on living tumor cells with europium emission’, Dalton Transactions., 2013, 42, 13495. (影响因子 = 4.029；中科院JCR分区：化学2区)
7) J. Zhang, H. Li, C.-F. Chan, R. Lan, W.-L. Chan, G.-L. Law, W.-K. Wong, K.-L. Wong, ‘A potential water-soluble ytterbium-based porphyrin-cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy’, Chemical Communications, 2012, 48, 9646. (共同第一作者；影响因子 = 6.319；中科院JCR分区：化学 1区)
8) Z. Zhao, P.-S. Chan, H. Li, K.-L.Wong, R. N. S. Wong, N.-K. Mak, J. Zhang, H.-L. Tam, W.-Y. Wong, D. W J Kwong, W.-K. Wong, ‘Highly selective mitochondria-targeting amphiphilic silicon(IV) phthalocyanines with axially ligated rhodamine B for photodynamic therapy.’ Inorganic Chemistry. 2012, 51, 812. (共同第一作者；影响因子 = 4.857；中科院JCR分区：无机化学与核化学 1区)
9) Y. Zhang, Y. Liu, X. Ma, X. Ma, B. Wang, H. Li, Y. Huang, C. Liu, ‘An environmentally friendly approach to the green synthesis of azo dyes with aryltriazenes via ionic liquid promoted C-N bonds formation’ Dyes and Pigments (影响因子 = 3.473; 中科院JCR分区：应用化学2区)
10) G. Bao, S. Zha, Z. Liu, Y.-H. Fung, C.-F. Chan, H. Li, P.-H. Chu, D. Jin, P. A. Tanner, K.-L. Wong, ‘Reversible and sensitive Hg2+ detection by cell permeable ytterbium complex’ Inorganic Chemistry. 2018, 57, 120. (影响因子 = 4.857；中科院JCR分区：无机化学与核化学 1区)
11) L. Jiang, R. Lan, T. Huang, C.-F. Chan, H. Li, S. Lear, J. Zong, W.-Y. Wong, M. M.-L. Lee, B. D. Chan, W.-L. Chan, W.-S. Lo, N.-K. Mak, M. L. Lung, H. L. Lung, S. W. Tsao, G. S T., Z.-X. Bian, W. CS Tai, G.-L. Law, W.-T. Wong, S. L. Cobb, K.-L. Wong, ‘EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein–Barr virus’, Nature Biomedical Engineering 2017, 1, 0042.
12) W.-S. Lo, H. Li, G.-L. Law, W.-T. Wong, K.-L. Wong, ‘Efficient and selective singlet oxygen sensitized NIR luminescence of a neodymium(III) complex and its application in biological imaging’, Journal of Luminescence, 2016, 169, 549. (影响因子 = 2.686；中科院JCR分区：物理2区)
13) D. Qi, Q. Wang, H. Li, T. Zhang, R. Lan, D. W J Kwong, W.-K. Wong, K.-L. Wong, S. Li, F. Lu, ‘SILAC-based quantitative proteomics identified lysosome as a fast response target to PDT agent Gd-N induced oxidative stress in human ovarian cancer IGROV1 cells’, Molecular BioSystems, 2015,11, 3059. (影响因子 = 2.781；中科院JCR分区：生物3区)
14) L. Jiang, Y.-L. Lui, H. Li, C.-F. Chan, R. Lan, W.-L. Chan, T. C.-K. Lau, G. S.-W. Tsao, N.-K. Mak and K.-L. Wong, ‘EBNA1-specific luminescent small molecules for the imaging and inhibition of latent EBV-infected tumor cells’, Chemical Communications, 2014, 50, 6517. (影响因子 = 6.319；中科院JCR分区：化学 1区)
15) C.-F. Chan, M.-K. Tsang, H. Li, R. Lan, F. L Chadbourne, W.-L. Chan, G.-L. Law, S. L. Cobb, J.-H. Hao, W.-T. Wong, K.-L. Wong, ‘Bifunctional up-converting lanthanide nanoparticles for selective in vitro imaging and inhibition of cyclin D as anti-cancer agents’, Journal of Materials Chemistry B, 2014, 2, 84. (影响因子 = 4.543；中科院JCR分区：工程技术1区)
16) T. Zhang, C.-F. Chan, R. Lan, H. Li, N.-K. Mak, W.-K. Wong and K.-L. Wong, ‘Porphyrin-based ytterbium complexes targeting anionic phospholipid membranes as selective biomarkers for cancer cell imaging’, Chemical Communications, 2013, 49, 7258. (影响因子 = 6.319；中科院JCR分区：化学1区)
17) C.-F. Chan, H. Li, C. Seto, H.-L. Tam, G.-L. Law, K.-L. Wong, ‘Synthesis, characterization, photophysical properties of lanthanide complexes with flexible tripodal carboxylate ligands’, Polyhedron, 2013, 50, 939. (影响因子 = 1.926；中科院JCR分区：化学3区)
18) S. He, H. Li, Y.-W. Yip, C.-T. Yeung, Y. O. Fung, H.-K. Kong, H.-L. Yeung, G.-L. Law, K.-L. Wong, C.-S. Lee, M. H.-W. Lam, M. B. Murphy, P. K.-S. Lam, W.-T. Wong, ‘Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin.’ Organic Letters, 2011, 13, 5036. (影响因子 = 6.579；中科院JCR分区：化学1区)
19) W. Wu, H.-K. Kong, H. Li, Y.-M. Ho, Y. Gao, J. Hao, M. B. Murphy, M. H.-W. Lam, K.-L. Wong, C.-S. Lee, ‘Comparative studies of multi‐photon induced emission by pyridine‐based small molecular probes in biological media: selective binding of bioactive molecules and in vitro imaging.’ European Journal of Organic Chemistry, 2011, 26, 5054. (影响因子 = 2.834；中科院JCR分区：化学3区)
20) H.-K. Kong, F. L Chadbourne, G.-L. Law, H. Li, H.-L. Tam, S. L. Cobb, C.-K. Lau, C.-S. Lee, K.-L. Wong, ‘Two-photon induced responsive f-f emissive detection of Cyclin A with a europium-chelating peptide.’ Chemical Communications, 2011, 47, 8052. (影响因子 = 6.319；中科院JCR分区：化学1区)
21) D. D. Lu, J. C. Yuan, H. Li, Z.-Q. Lei, ‘Synthesis and characterization of a series of biodegradable and biocompatible PEG‐supported poly(lactic‐ran‐glycolic acid) amphiphilic barbell‐like copolymers’, Journal of Polymer Science Part A: Polymer Chemistry, 2008, 46, 3802. (影响因子 = 2.952；中科院JCR分区：高分子科学2区)
专利
1. K.-L. Wong, H. Li, C. F. Chan, R. Lan, Lanthanide toolbox for organelle specific molecular imaging’ US Patent 20,170,342,090.
2. K. L. Wong, H. Li, ‘A lanthanide toolbox for multi-modal, non-invasive tumor specific theranostic prodrugs’ US Patent filled no. 62/397,360.